This book gathers revised papers presented at the 2024 International Symposium of the Business Systems Laboratory, held in Palermo, Italy on January 11-12, 2024. In the last four years, the world has seen dramatic changes in virtually every aspect of global society. We have seen a rapid transformation of social systems and, since the outbreak of COVID-19 in 2020, an unprecedented acceleration of the socioeconomic upheavals already in place - disruptive socioeconomic changes that have since been dubbed "The Great Reset" by the World Economic Forum. The book applies scientific rigor to discuss and debate these disruptive transformations and identify new ways to address the global economic and social challenges of our time from a systemic perspective. It sheds light on the various interactions between natural, social, and economic systems in these turbulent times by pursuing a multidisciplinary but integrative approach that encompasses e.g. management, information science, psychology, economics, engineering, and political science. Accordingly, the book will be of interest to readers from these fields, from both an academic and managerial standpoint.