"Don't go to the rescue centers." An emerging Totalitarian Government unleashes a population-reducing horror upon the Earth. Would you bug in or bug out when faced with the probability both choices would end in death, imprisonment, or worse? As neighborhoods and hospitals become war zones and panicked citizens create gridlock in search of anywhere safe, the Danburys decide to bug in with their teenage daughter Natalie until the chaos dies down enough for them to escape to a rumored sanctuary in the mountains. They enlist the carpentry skills of Coltan, a brutally abused young man they befriended, to secure their home and create a hiding place within it. Meanwhile in the impoverished south end of town, young Mario Rodriquez fights through the hordes of infected to rescue his mother and his younger sister Rosa.