The murder in mysterious circumstances of Doctor Jannie de Villiers, a well known liver transplant surgeon, in Cape Town South Africa in 1993, sets in train an epic adventure for his son. Christian de Villiers who was taken to Australia by his mother after his father's death, decides to return sixteen years later to investigate how his father died and finds that he was deeply involved with the brutal enforcing agency of the old apartheid government, the Bureau of State Security (BOSS).

The discovery of a folder buried in the backyard of his old home which contains his fathers genetic research into the black and coloured populations and details how those population groups may be controlled through genetic targeting. The folder also documents South Africa's cooperation with other nations in the development of nuclear weapons, and its involvement in the development of germ and chemical warfare agents .This discovery causes Christian and his newly discovered half sister Isabella to become targets for the National Intelligence agency, who fear information in the folder may embarrass foreign governments. While trying to work out what to do with the folder Christian and Isabella are imprisoned by a secret white supremacist group intent on utilising the genetic research to re-establish a White homeland in South Africa.