The present study was focussed on the development of integrated database of bioactive peptides of milk proteins and other resources, in-silico study of the structures, phylogeny and conserved domains of different bioactive peptides. The developed the integrated database of different bioactive peptides viz. antithrombotic, antimicrobial, opioid, immunomodulatory, mineral binding peptides was developed. In present work, the back end of the above stated database was developed into MSAccess then front end is in JSP, JSS and HTML. This database will be helpful to the researchers working on bioactive peptides. It comprises an information associated to bioactive molecules like Gene-ID, common and scientific name etc. and has significant description of biological process, molecular function and cellular component. Subsequently, feasible structures of bioactive peptides were also designed by using homology approach. For this purpose online server of swiss modal, swiss templates along with swiss repository was used